LmrR: A Privileged Scaffold for Artificial Metalloenzymes
نویسندگان
چکیده
منابع مشابه
Artificial metalloenzymes for enantioselective catalysis.
Artificial metalloenzymes have emerged over the last decades as an attractive approach towards combining homogeneous catalysis and biocatalysis. A wide variety of catalytic transformations have been established by artificial metalloenzymes, thus establishing proof of concept. The field is now slowly transforming to take on new challenges. These include novel designs, novel catalytic reactions, ...
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Catalysis is the most efficient strategy for the preparation of enantiopure products. Homogeneous and enzymatic catalyses are in many respects complementary in terms of substrate and reaction scope, operating conditions, enantioselection mechanism, etc. In terms of performance optimization, directed evolution methodologies outperform combinatorial ligand libraries. With the aim of combining the...
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Enantioselective catalysis is one of the most efficient ways to synthesize high-added-value enantiomerically pure organic compounds. As the subtle details which govern enantioselection cannot be reliably predicted or computed, catalysis relies more and more on a combinatorial approach. Biocatalysis offers an attractive, and often complementary, alternative for the synthesis of enantiopure produ...
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ژورنال
عنوان ژورنال: Accounts of Chemical Research
سال: 2019
ISSN: 0001-4842,1520-4898
DOI: 10.1021/acs.accounts.9b00004